Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##an astonishing scandal involving people desperate for cheap drugs, "meaningless" efforts made by individuals, "evil" companies, historically do-nothing FDA, politics and poor regulations. yet sadly the same story will happen again and again and again.
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评分##问题本身并不仅限于药企,本质上是policymaker和lawmaker如何能改良现有框架适应全球化,要不然迟早是下一个罗马。
评分##investigative journalism比侦探悬疑武侠都好读!本来是要坚定信心好好赚钱just so that I can pay whatever for the non generics,后面读到drug resistance那段觉得也无所谓了,????大家一起玩完。
评分##https://athenacool.wordpress.com/2019/05/21/bottle-of-lies/
评分##问题本身并不仅限于药企,本质上是policymaker和lawmaker如何能改良现有框架适应全球化,要不然迟早是下一个罗马。
评分##首先,非常感谢作者在经过大量的访谈和研究之后写出这么一本精彩的书,很不易。其次,作者选择的话题让我震惊。真的是用震惊来形容都不过!都感觉不象是非虚构作品,而是一本惊悚小说。印度制药界是没有良心可言的,他们认为撒谎,作假是正常的,因为整个社会都是这样,有什么好奇怪的。就算是铁证如山,他们仍旧可以平静地看着你的眼睛,说,没有啊?这药好好的呀。FDA实在是机构臃肿,办事非常不利索。如果没有最出的whistler blower和自己的好员工,那么这个药厂的丑闻还不知道什么时候才能被揭露,而又会又多少病人因为药的不合格而死去。最后,这本书写得非常棒,文字功底厚,结构条例清晰。强烈推荐给任何对健康重视的人士。
评分##做了心理建设还是很难相信这种肮脏勾当是广泛存在的,FDA的形式主义和无所作为也是视人命如草芥
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