Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
触目惊心,我国石家庄一家药企“上榜”,生产的无效头孢在非洲致儿童死亡,中文版里不知能否保留
评分##这本书给我感觉和bad blood很像,也是一个记者多方访谈追踪揭露制药厂的骗局,读下来触目惊心,一遍遍问这是真的吗?真的吗?怎么会这样?FDA完全不可信了?简单结论就是千万不要再吃generic drugs了!
评分##这本书给我感觉和bad blood很像,也是一个记者多方访谈追踪揭露制药厂的骗局,读下来触目惊心,一遍遍问这是真的吗?真的吗?怎么会这样?FDA完全不可信了?简单结论就是千万不要再吃generic drugs了!
评分##investigative journalism比侦探悬疑武侠都好读!本来是要坚定信心好好赚钱just so that I can pay whatever for the non generics,后面读到drug resistance那段觉得也无所谓了,????大家一起玩完。
评分##首先,非常感谢作者在经过大量的访谈和研究之后写出这么一本精彩的书,很不易。其次,作者选择的话题让我震惊。真的是用震惊来形容都不过!都感觉不象是非虚构作品,而是一本惊悚小说。印度制药界是没有良心可言的,他们认为撒谎,作假是正常的,因为整个社会都是这样,有什么好奇怪的。就算是铁证如山,他们仍旧可以平静地看着你的眼睛,说,没有啊?这药好好的呀。FDA实在是机构臃肿,办事非常不利索。如果没有最出的whistler blower和自己的好员工,那么这个药厂的丑闻还不知道什么时候才能被揭露,而又会又多少病人因为药的不合格而死去。最后,这本书写得非常棒,文字功底厚,结构条例清晰。强烈推荐给任何对健康重视的人士。
评分##触目惊心,肺炎疫情期间看更有额外的感慨。关于天朝那一段估计中文版会删吧……
评分##一个这么好的题材,被作者写得稀烂。故事非常散乱且冗长。有种所有我调查到的内容都要填进去的杂乱感。人物脸谱化,凡正面角色一定要讲到成长经历,父亲职业的影响,反面角色一定是生活奢迷,草菅人命,毫无道德可言。350字装不下我的吐槽。可能需要写一篇长评。。。。。。
评分##简直是触目惊心的一本书,4.5星,半星给写作的重复性打折掉。但是看到原本应该一丝不苟的制药业居然如此的藏污纳垢,药性与原厂药不能相比就不说了,篡改伪造数据也不说了,制药环境居然如此恶劣,而厂商以及质监局的态度又是如此的nonchalant,对待监察力度很弱而便宜仿制药需求又很大的第三世界的人命如此淡漠,相关人员只图暴利而不把民众的安全和性命当一回事,最后却也没有得到法律制裁的种种事情实在是让人发指!立马把家长吃的药赶快拿来查一下是不是也有质量不过关的问题。。。
评分##bad blood, billion dollar whale... fraud seems everywhere and beyond my wild imagination... one whistle blower against the world.. how many of us are brave enough to do this? luckily sometimes one would be sufficient
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