Bottle of Lies: The Inside Story of the Generic Drug Boom

Bottle of Lies: The Inside Story of the Generic Drug Boom pdf epub mobi txt 电子书 下载 2025

Katherine Eban
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具体描述

Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?

Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.

The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?

A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

用户评价

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##https://athenacool.wordpress.com/2019/05/21/bottle-of-lies/

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##优点是:1 故事精彩,特别是Ranbaxy部分 2 对仿制药的出现和问题的支出,在4+7时代尤其重要。缺点是:1 太多采访驱动,数据太少,导致面子太多里子不够 2 野心太大导致主线太散

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##触目惊心,肺炎疫情期间看更有额外的感慨。关于天朝那一段估计中文版会删吧……

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##问题本身并不仅限于药企,本质上是policymaker和lawmaker如何能改良现有框架适应全球化,要不然迟早是下一个罗马。

评分

##做了心理建设还是很难相信这种肮脏勾当是广泛存在的,FDA的形式主义和无所作为也是视人命如草芥

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##医药版本的长夜难明。

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##an astonishing scandal involving people desperate for cheap drugs, "meaningless" efforts made by individuals, "evil" companies, historically do-nothing FDA, politics and poor regulations. yet sadly the same story will happen again and again and again.

评分

##问题本身并不仅限于药企,本质上是policymaker和lawmaker如何能改良现有框架适应全球化,要不然迟早是下一个罗马。

评分

##做了心理建设还是很难相信这种肮脏勾当是广泛存在的,FDA的形式主义和无所作为也是视人命如草芥

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