Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##这本书像一个加长版bad blood 都是从上到下做假 不在意生产过程 该work的行业标杆FDA水土不服监管失灵 whistle blower心惊胆战地揭秘但是调查迟缓 可以感受到对global south的凝视 印象最深刻的是对whistle blower的比喻:大家都听说过可是没有人见过他们
评分##这本书给我感觉和bad blood很像,也是一个记者多方访谈追踪揭露制药厂的骗局,读下来触目惊心,一遍遍问这是真的吗?真的吗?怎么会这样?FDA完全不可信了?简单结论就是千万不要再吃generic drugs了!
评分##简直是触目惊心的一本书,4.5星,半星给写作的重复性打折掉。但是看到原本应该一丝不苟的制药业居然如此的藏污纳垢,药性与原厂药不能相比就不说了,篡改伪造数据也不说了,制药环境居然如此恶劣,而厂商以及质监局的态度又是如此的nonchalant,对待监察力度很弱而便宜仿制药需求又很大的第三世界的人命如此淡漠,相关人员只图暴利而不把民众的安全和性命当一回事,最后却也没有得到法律制裁的种种事情实在是让人发指!立马把家长吃的药赶快拿来查一下是不是也有质量不过关的问题。。。
评分##[audible]
评分##优点是:1 故事精彩,特别是Ranbaxy部分 2 对仿制药的出现和问题的支出,在4+7时代尤其重要。缺点是:1 太多采访驱动,数据太少,导致面子太多里子不够 2 野心太大导致主线太散
评分##bad blood, billion dollar whale... fraud seems everywhere and beyond my wild imagination... one whistle blower against the world.. how many of us are brave enough to do this? luckily sometimes one would be sufficient
评分##这本书给我感觉和bad blood很像,也是一个记者多方访谈追踪揭露制药厂的骗局,读下来触目惊心,一遍遍问这是真的吗?真的吗?怎么会这样?FDA完全不可信了?简单结论就是千万不要再吃generic drugs了!
评分##an astonishing scandal involving people desperate for cheap drugs, "meaningless" efforts made by individuals, "evil" companies, historically do-nothing FDA, politics and poor regulations. yet sadly the same story will happen again and again and again.
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