具體描述
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
用戶評價
##Generic drugs still have a long way to go
評分##闊怕 保命請認準大廠原研藥 以及第三世界真實從頭慘到腳
評分##這本書像一個加長版bad blood 都是從上到下做假 不在意生産過程 該work的行業標杆FDA水土不服監管失靈 whistle blower心驚膽戰地揭秘但是調查遲緩 可以感受到對global south的凝視 印象最深刻的是對whistle blower的比喻：大傢都聽說過可是沒有人見過他們
評分##做瞭心理建設還是很難相信這種骯髒勾當是廣泛存在的，FDA的形式主義和無所作為也是視人命如草芥
評分##看到在FDA調查員住的酒店裝監聽器真的看得我毛骨悚然，後麵真的心疼baker和thakur。一個辛辛苦苦找fraudelence的證據後給齣OAI，agency卻為瞭指標downgrade to VAI，lift ban...一個為瞭正義做whistleblower，說因此導緻妻離子散，傢破人亡也不為過。 難道隻要有藥，就可以不論質量地給病人吃嗎。 如果代錶著最高標準的FDA都是這樣讓人心寒，我們還能相信誰。難道以後大傢保命隻能花巨額買brand-name嗎.. 對lal，baker，thakur等戰士錶示敬意，對Katherine Eban在內的所有調查記者緻以敬意。因為他們，我們纔離真相越來越近。也因此看清瞭善與惡的對抗不過是以卵擊石。一切正義行為在利益麵前都是如此不堪一擊。
評分##這本書給我感覺和bad blood很像，也是一個記者多方訪談追蹤揭露製藥廠的騙局，讀下來觸目驚心，一遍遍問這是真的嗎？真的嗎？怎麼會這樣？FDA完全不可信瞭？簡單結論就是韆萬不要再吃generic drugs瞭！
評分##這本書給我感覺和bad blood很像，也是一個記者多方訪談追蹤揭露製藥廠的騙局，讀下來觸目驚心，一遍遍問這是真的嗎？真的嗎？怎麼會這樣？FDA完全不可信瞭？簡單結論就是韆萬不要再吃generic drugs瞭！
評分##讀瞭三分之二終究還是決定放棄瞭????一個理科生隻想看是啥原理導緻仿製藥的巨大問題，卻不太想知道中間那麼多復雜而又牽扯巨多的故事細節????????????然鵝這本書連uplcms都要解釋一下但沒解釋清楚。。。
評分##一個這麼好的題材，被作者寫得稀爛。故事非常散亂且冗長。有種所有我調查到的內容都要填進去的雜亂感。人物臉譜化，凡正麵角色一定要講到成長經曆，父親職業的影響，反麵角色一定是生活奢迷，草菅人命，毫無道德可言。350字裝不下我的吐槽。可能需要寫一篇長評。。。。。。
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