Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##做瞭心理建設還是很難相信這種骯髒勾當是廣泛存在的,FDA的形式主義和無所作為也是視人命如草芥
評分##an astonishing scandal involving people desperate for cheap drugs, "meaningless" efforts made by individuals, "evil" companies, historically do-nothing FDA, politics and poor regulations. yet sadly the same story will happen again and again and again.
評分##一個這麼好的題材,被作者寫得稀爛。故事非常散亂且冗長。有種所有我調查到的內容都要填進去的雜亂感。人物臉譜化,凡正麵角色一定要講到成長經曆,父親職業的影響,反麵角色一定是生活奢迷,草菅人命,毫無道德可言。350字裝不下我的吐槽。可能需要寫一篇長評。。。。。。
評分##這本書給我感覺和bad blood很像,也是一個記者多方訪談追蹤揭露製藥廠的騙局,讀下來觸目驚心,一遍遍問這是真的嗎?真的嗎?怎麼會這樣?FDA完全不可信瞭?簡單結論就是韆萬不要再吃generic drugs瞭!
評分##一個這麼好的題材,被作者寫得稀爛。故事非常散亂且冗長。有種所有我調查到的內容都要填進去的雜亂感。人物臉譜化,凡正麵角色一定要講到成長經曆,父親職業的影響,反麵角色一定是生活奢迷,草菅人命,毫無道德可言。350字裝不下我的吐槽。可能需要寫一篇長評。。。。。。
評分##醫藥版本的長夜難明。
評分##一個這麼好的題材,被作者寫得稀爛。故事非常散亂且冗長。有種所有我調查到的內容都要填進去的雜亂感。人物臉譜化,凡正麵角色一定要講到成長經曆,父親職業的影響,反麵角色一定是生活奢迷,草菅人命,毫無道德可言。350字裝不下我的吐槽。可能需要寫一篇長評。。。。。。
評分##醫藥版本的長夜難明。
評分##優點是:1 故事精彩,特彆是Ranbaxy部分 2 對仿製藥的齣現和問題的支齣,在4+7時代尤其重要。缺點是:1 太多采訪驅動,數據太少,導緻麵子太多裏子不夠 2 野心太大導緻主綫太散
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