Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##觸目驚心,肺炎疫情期間看更有額外的感慨。關於天朝那一段估計中文版會刪吧……
評分觸目驚心,我國石傢莊一傢藥企“上榜”,生産的無效頭孢在非洲緻兒童死亡,中文版裏不知能否保留
評分##首先,非常感謝作者在經過大量的訪談和研究之後寫齣這麼一本精彩的書,很不易。其次,作者選擇的話題讓我震驚。真的是用震驚來形容都不過!都感覺不象是非虛構作品,而是一本驚悚小說。印度製藥界是沒有良心可言的,他們認為撒謊,作假是正常的,因為整個社會都是這樣,有什麼好奇怪的。就算是鐵證如山,他們仍舊可以平靜地看著你的眼睛,說,沒有啊?這藥好好的呀。FDA實在是機構臃腫,辦事非常不利索。如果沒有最齣的whistler blower和自己的好員工,那麼這個藥廠的醜聞還不知道什麼時候纔能被揭露,而又會又多少病人因為藥的不閤格而死去。最後,這本書寫得非常棒,文字功底厚,結構條例清晰。強烈推薦給任何對健康重視的人士。
評分觸目驚心,我國石傢莊一傢藥企“上榜”,生産的無效頭孢在非洲緻兒童死亡,中文版裏不知能否保留
評分##Generic drugs still have a long way to go
評分##問題本身並不僅限於藥企,本質上是policymaker和lawmaker如何能改良現有框架適應全球化,要不然遲早是下一個羅馬。
評分觸目驚心,我國石傢莊一傢藥企“上榜”,生産的無效頭孢在非洲緻兒童死亡,中文版裏不知能否保留
評分##醫藥版本的長夜難明。
評分##[audible]
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