Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##首先,非常感謝作者在經過大量的訪談和研究之後寫齣這麼一本精彩的書,很不易。其次,作者選擇的話題讓我震驚。真的是用震驚來形容都不過!都感覺不象是非虛構作品,而是一本驚悚小說。印度製藥界是沒有良心可言的,他們認為撒謊,作假是正常的,因為整個社會都是這樣,有什麼好奇怪的。就算是鐵證如山,他們仍舊可以平靜地看著你的眼睛,說,沒有啊?這藥好好的呀。FDA實在是機構臃腫,辦事非常不利索。如果沒有最齣的whistler blower和自己的好員工,那麼這個藥廠的醜聞還不知道什麼時候纔能被揭露,而又會又多少病人因為藥的不閤格而死去。最後,這本書寫得非常棒,文字功底厚,結構條例清晰。強烈推薦給任何對健康重視的人士。
評分##醫藥版本的長夜難明。
評分##一個這麼好的題材,被作者寫得稀爛。故事非常散亂且冗長。有種所有我調查到的內容都要填進去的雜亂感。人物臉譜化,凡正麵角色一定要講到成長經曆,父親職業的影響,反麵角色一定是生活奢迷,草菅人命,毫無道德可言。350字裝不下我的吐槽。可能需要寫一篇長評。。。。。。
評分##Generic drugs still have a long way to go
評分##讀瞭三分之二終究還是決定放棄瞭????一個理科生隻想看是啥原理導緻仿製藥的巨大問題,卻不太想知道中間那麼多復雜而又牽扯巨多的故事細節????????????然鵝這本書連uplcms都要解釋一下但沒解釋清楚。。。
評分##簡直是觸目驚心的一本書,4.5星,半星給寫作的重復性打摺掉。但是看到原本應該一絲不苟的製藥業居然如此的藏汙納垢,藥性與原廠藥不能相比就不說瞭,篡改僞造數據也不說瞭,製藥環境居然如此惡劣,而廠商以及質監局的態度又是如此的nonchalant,對待監察力度很弱而便宜仿製藥需求又很大的第三世界的人命如此淡漠,相關人員隻圖暴利而不把民眾的安全和性命當一迴事,最後卻也沒有得到法律製裁的種種事情實在是讓人發指!立馬把傢長吃的藥趕快拿來查一下是不是也有質量不過關的問題。。。
評分##an astonishing scandal involving people desperate for cheap drugs, "meaningless" efforts made by individuals, "evil" companies, historically do-nothing FDA, politics and poor regulations. yet sadly the same story will happen again and again and again.
評分##醫藥版本的長夜難明。
評分##做瞭心理建設還是很難相信這種骯髒勾當是廣泛存在的,FDA的形式主義和無所作為也是視人命如草芥
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