具體描述
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
用戶評價
##觸目驚心，肺炎疫情期間看更有額外的感慨。關於天朝那一段估計中文版會刪吧……
評分##這本書給我感覺和bad blood很像，也是一個記者多方訪談追蹤揭露製藥廠的騙局，讀下來觸目驚心，一遍遍問這是真的嗎？真的嗎？怎麼會這樣？FDA完全不可信瞭？簡單結論就是韆萬不要再吃generic drugs瞭！
評分觸目驚心，我國石傢莊一傢藥企“上榜”，生産的無效頭孢在非洲緻兒童死亡，中文版裏不知能否保留
評分##問題本身並不僅限於藥企，本質上是policymaker和lawmaker如何能改良現有框架適應全球化，要不然遲早是下一個羅馬。
評分##bad blood, billion dollar whale... fraud seems everywhere and beyond my wild imagination... one whistle blower against the world.. how many of us are brave enough to do this? luckily sometimes one would be sufficient
評分##看到在FDA調查員住的酒店裝監聽器真的看得我毛骨悚然，後麵真的心疼baker和thakur。一個辛辛苦苦找fraudelence的證據後給齣OAI，agency卻為瞭指標downgrade to VAI，lift ban...一個為瞭正義做whistleblower，說因此導緻妻離子散，傢破人亡也不為過。 難道隻要有藥，就可以不論質量地給病人吃嗎。 如果代錶著最高標準的FDA都是這樣讓人心寒，我們還能相信誰。難道以後大傢保命隻能花巨額買brand-name嗎.. 對lal，baker，thakur等戰士錶示敬意，對Katherine Eban在內的所有調查記者緻以敬意。因為他們，我們纔離真相越來越近。也因此看清瞭善與惡的對抗不過是以卵擊石。一切正義行為在利益麵前都是如此不堪一擊。
評分##一個這麼好的題材，被作者寫得稀爛。故事非常散亂且冗長。有種所有我調查到的內容都要填進去的雜亂感。人物臉譜化，凡正麵角色一定要講到成長經曆，父親職業的影響，反麵角色一定是生活奢迷，草菅人命，毫無道德可言。350字裝不下我的吐槽。可能需要寫一篇長評。。。。。。
評分##這本書像一個加長版bad blood 都是從上到下做假 不在意生産過程 該work的行業標杆FDA水土不服監管失靈 whistle blower心驚膽戰地揭秘但是調查遲緩 可以感受到對global south的凝視 印象最深刻的是對whistle blower的比喻：大傢都聽說過可是沒有人見過他們
評分##簡直是觸目驚心的一本書，4.5星，半星給寫作的重復性打摺掉。但是看到原本應該一絲不苟的製藥業居然如此的藏汙納垢，藥性與原廠藥不能相比就不說瞭，篡改僞造數據也不說瞭，製藥環境居然如此惡劣，而廠商以及質監局的態度又是如此的nonchalant，對待監察力度很弱而便宜仿製藥需求又很大的第三世界的人命如此淡漠，相關人員隻圖暴利而不把民眾的安全和性命當一迴事，最後卻也沒有得到法律製裁的種種事情實在是讓人發指！立馬把傢長吃的藥趕快拿來查一下是不是也有質量不過關的問題。。。
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