具體描述
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
用戶評價
##簡直是觸目驚心的一本書，4.5星，半星給寫作的重復性打摺掉。但是看到原本應該一絲不苟的製藥業居然如此的藏汙納垢，藥性與原廠藥不能相比就不說瞭，篡改僞造數據也不說瞭，製藥環境居然如此惡劣，而廠商以及質監局的態度又是如此的nonchalant，對待監察力度很弱而便宜仿製藥需求又很大的第三世界的人命如此淡漠，相關人員隻圖暴利而不把民眾的安全和性命當一迴事，最後卻也沒有得到法律製裁的種種事情實在是讓人發指！立馬把傢長吃的藥趕快拿來查一下是不是也有質量不過關的問題。。。
評分##闊怕 保命請認準大廠原研藥 以及第三世界真實從頭慘到腳
評分##bad blood, billion dollar whale... fraud seems everywhere and beyond my wild imagination... one whistle blower against the world.. how many of us are brave enough to do this? luckily sometimes one would be sufficient
評分##an astonishing scandal involving people desperate for cheap drugs, "meaningless" efforts made by individuals, "evil" companies, historically do-nothing FDA, politics and poor regulations. yet sadly the same story will happen again and again and again.
評分##[audible]
評分##觸目驚心，肺炎疫情期間看更有額外的感慨。關於天朝那一段估計中文版會刪吧……
評分##優點是：1 故事精彩，特彆是Ranbaxy部分 2 對仿製藥的齣現和問題的支齣，在4+7時代尤其重要。缺點是：1 太多采訪驅動，數據太少，導緻麵子太多裏子不夠 2 野心太大導緻主綫太散
評分##看到在FDA調查員住的酒店裝監聽器真的看得我毛骨悚然，後麵真的心疼baker和thakur。一個辛辛苦苦找fraudelence的證據後給齣OAI，agency卻為瞭指標downgrade to VAI，lift ban...一個為瞭正義做whistleblower，說因此導緻妻離子散，傢破人亡也不為過。 難道隻要有藥，就可以不論質量地給病人吃嗎。 如果代錶著最高標準的FDA都是這樣讓人心寒，我們還能相信誰。難道以後大傢保命隻能花巨額買brand-name嗎.. 對lal，baker，thakur等戰士錶示敬意，對Katherine Eban在內的所有調查記者緻以敬意。因為他們，我們纔離真相越來越近。也因此看清瞭善與惡的對抗不過是以卵擊石。一切正義行為在利益麵前都是如此不堪一擊。
評分##investigative journalism比偵探懸疑武俠都好讀！本來是要堅定信心好好賺錢just so that I can pay whatever for the non generics，後麵讀到drug resistance那段覺得也無所謂瞭，????大傢一起玩完。
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