From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting book shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls readers to consider a future where aging can be treated. For decades, experts have believed that we are at the mercy of our genes, and that natural damage to our genes—the kind that inevitably happens as we get older—makes us become sick and grow old. But what if everything you think you know about aging is wrong? What if aging is a disease—and that disease is treatable? In Lifespan, one of the world’s foremost experts on aging and genetics reveals a groundbreaking new theory that will forever change the way we think about why we age and what we can do about it. Aging isn’t immutable; we can have far more control over it than we realize. This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab—that demonstrate how we can slow down, or even reverse, the genetic clock. The key is activating newly discovered vitality genes—the decedents of an ancient survival circuit that is both the cause of aging and the key to reversing it. Dr. Sinclair shares the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, and exercising with the right intensity—that have been shown to help lead to longer lives. Lifespan provides a roadmap for taking charge of our own health destiny and a bold new vision for the future when humankind is able to live to be 100 years young.
##还不错,给人很多的希望可以不老,以至于长生。过去和现在写得有血有肉。未来有点重复。不吃,少吃糖,多吃蔬菜,少吃红肉,吃一定的营养品,锻炼,延缓衰老。
评分##Looks like David wrote the book in a rush. It's supposed to be a book describing the theory of aging, but he spent a lot of efforts explaining how modern healthcare is changing..
评分空话连篇……就一个建议可行:少吃点东西。另外推荐了三样东西:白藜芦醇,二甲双胍,烟酰胺单核苷酸。除了二甲双胍,另外两种的吸收和利用率都很成问题。整本书还不如他参加Joe Rogan的那期采访的干货多。其实真的内容写篇博文三四页纸就够了,这非死乞白赖凑出本书来。
评分##intermittent fasting, cold exposure, exercising with right intensity, eating less meat
评分##其实内容也还行,虽然贩售程度和内容可靠程度不完全匹配,但科学本身并没有硬伤。但是这本书实在不能吸引我,而且我也很不喜欢里面时不时出现一下的“采访”场景,刻意而没有必要。
评分##文字优美,但是也太拖沓了吧。
评分##长寿的三个秘诀:适度可控的饥饿,寒冷和高强度运动
评分##啰嗦得不行,google了一下information theory of aging 的图片,然后里面搜到一个论文一个图表总结了作者吃什么补剂,lifestyle(间歇性断食,限制碳水,少吃红肉多吃素,锻炼,避免过度暴露于紫外线、X光、CT, 不抽烟,cold exposure, 维持BMI,除了补剂没有什么新意,一查作者果然有不少利益冲突。当然NMN可以通过亲身体验判断下,不过上面这个lifestypd的变量太多,同时变化就没法测NMN的功效了。 https://www.researchgate.net/publication/343562143_The_information_theory_of_aging_Hacking_immortality
评分##写到一半开始混乱
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